Colin Egglesfield has been candid about his experience battling cancer through the years.
Egglesfield was first diagnosed with testicular cancer in 2006 amid his run on All My Children. After going into remission, the actor’s testicular cancer recurred the next year. He was diagnosed with prostate cancer 17 years later in 2024.
“After [I was firs] diagnosed with it, it’s just a very scary experience because it’s all the fear of the unknown,” the Something Borrowed star exclusively told Us Weekly in June 2019. “I didn’t know what to expect.”
Keep scrolling for Egglesfield’s candid comments about his cancer journey in his own words:
‘Could Be the End’
“One of the biggest pieces of advice I got was from my mom, after I got diagnosed for the second time,” Egglesfield told Us in 2019. “At that point, I literally thought that it could be the end. I remember calling her up one day and I broke down and she was like, ‘Colin, you may not be able to deal with this. But you need to be a warrior. You need to put your armor on and you need to go to battle now.’”
He continued, “Once she gave me that context, it made me realize, you know what? I do, because otherwise this is too overwhelming and it could crush me. So that really helped.”
Diagnosed for a 3rd Time
Egglesfield revealed in January 2025 that he was diagnosed with prostate cancer one year prior.
“Thankfully, we caught my prostate cancer early and after a year of doing a lot of research and talking to quite a few health care professionals, I elected to be proactive and have surgery,” he wrote via Instagram. “Each day I’m getting healthier and stronger. I’m still a bit sore but I’m making progress and am determined to come back stronger and healthier than ever, especially with the help of my sexy walker.”
A Meaningful Support System
Egglesfield depended on his parents and his inner circle while receiving treatment.
“I learned early on from my parents that what you focus on grows. My mom believed in the power of possibility, by directing your time and energy toward good outcomes, you give yourself a fighting chance,” he told Preferred Health magazine in June 2025. “Focusing on negatives and ‘what ifs’ can be disempowering. To move through my cancer experience, I had to focus on healing.”
Egglesfield further revealed that a cancer diagnosis could also impact a romantic relationship.
“It’s easy to get trapped in romantic ideals, especially as an actor immersed in heightened realities,” he told the outlet. “But real love means being seen and supported for who you are. Romance and passion are essential, but what deepens them is knowing you’re with someone who is your best friend and will be there through the good, the bad and the ugly.”
According to Egglesfield, his girlfriend, Krista, was a major source of support.
“My girlfriend took care of me when I was at my weakest,” he said. “That deepened our connection and showed me what real love looks like. It’s helped me heal — and changed my life.”
Embracing Vulnerability
“I feel like once you are able to authentically talk about something that is scary and where you feel like you’re in this vulnerable place, but yet the people show up in your life that are there to support you, I felt like I didn’t have to hide,” he told People in July 2025. “I didn’t have to pretend to be brave and pretend to act like everything was OK.”
He added, “The mental component of dealing with any health challenge is so huge. I would say definitely surround yourself with people who you feel like you can share what you’re going through, who are going to listen, who are going to really create that safe space for you.”
Embracing Challenges
“If you lose your job, or if you face a health challenge like my cancer diagnoses, you learn to embrace these challenges and use your creativity to navigate them,” Egglesfield told Authority Magazine in December 2025. “Darwin said human beings are incredibly adaptable. The challenge is not to resist the obstacle because most people want to avoid pain. But the more you lean into the obstacle, the more you can figure out a way to solve it.
‘Grateful to be Here’
Egglesfield told E! News in January 2026 that he is “cancer-free.”
“I’m grateful to be here. I’m just grateful that I’m on the other side of it and able to now move on with my life,” he told the outlet. “It’ll be a year in February. Fortunately, they caught it early enough where I didn’t have to do any radiation or chemotherapy or anything and that’s one of the things that I just wanted to avoid.”
Egglesfield further revealed that he was still recovering from his prostatectomy, the surgical removal of his prostate gland.
“It hasn’t been an easy recovery because there’s learning how to go to the bathroom again, and erectile stuff,” he stated. “But knowing that I don’t have to deal with this in the future, and I can potentially move on, is something I’m super grateful for.”
