Through history, women have tried all sorts of strange remedies to help alleviate common menstrual symptoms like mood swings, pelvic pain and sudden fatigue.
Now, a new solution is here — and no surprise — it’s powered by artificial intelligence. Samphire Neuroscience offers personalized, at-home neurostimulation that adapts to women’s menstrual symptoms, helping them feel more balanced through hormonal changes.
On Feb. 9, the UK-based neurotechnology startup unveiled its latest feature in the health-tech space: a patented, AI-driven neurostimulation session-scheduling system.
The feature is called CycleSync, and it’s used in conjunction with Samphire’s wearable devices.
Samphire is already behind Nettle and Lutea, two wearable devices that support hormonal well-being through non-invasive neurostimulation. According to the brand, users can expect to feel relief with just one 20-minute session a day, for a few days out of every cycle.
The idea is simple: the brain controls key hormones like estrogen and progesterone, which impact the menstrual cycle and can cause symptoms such as mood swings, cravings, pain and fatigue. The brain also runs on electricity — rhythms that shape how you think, feel and respond.
By delivering targeted neurostimulation at the right time and dose, Samphire believes it could help keep women’s brains balanced during hormonal shifts.
That’s where CycleSync comes into play.
CycleSync, now available in the Samphire app, tracks user data over time, analyzing symptoms like fatigue, stress and anxiety. It also considers how symptoms change with ongoing neurostimulation use and incorporates user feedback, along with logged biological shifts such as cycle changes or ovulation.
As the algorithm picks up the patterns, neurostimulation session scheduling adapts accordingly, altering when and how sessions are scheduled. Users remain in full control and can pause or adjust scheduling at any time. The company affirms that user data is never sold; it’s used solely to understand real-world responses to neurostimulation.
With this new AI-powered feature, Samphire’s founders believe that they can continue to finetune treatment protocols for millions of women. The launch of CycleSync addresses a key reality that many companies miss altogether: not all women follow a predictable 28-day menstrual cycle.
“Our user data shows enormous variation in when symptoms appear and how people respond to neurostimulation,” said Dr Emilė Radytė, CEO of Samphire Neuroscience. “That data has enabled us to build personalized session scheduling that reflects reality, not outdated assumptions.”
Theoretically, CycleSync could be especially helpful for people living with endometriosis, PMDD, PMS, PCOS and other hormone-linked conditions.
Samphire already has the research to back many of its claims.
Several clinical studies have revealed that this kind of neurostimulation technology can help improve symptoms for those dealing with endometriosis-related pain, chronic pelvic pain and other hormone-related conditions.
A trial published in IEEE looked at those using Nettle for PMS and dysmenorrhea, finding that 67% of participants reported mood improvements within one cycle and 72% experienced reduced pain within the same period. About 97% of users also found Nettle easy to integrate into their lives.
“This is about treating people as individuals, not averages,” added Radytė. “By personalizing how neurostimulation sessions are scheduled, we’re setting a new standard for how at-home neurostimulation should work.”
Features like CycleSync are just the beginning of how women can benefit from this kind of neurotechnology. For now, Samphire remains a pioneer in a space that could change how women experience their menstrual cycle symptoms — forever.
This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson’s Blueprint Longevity Mix to the viral Oura Ring to Jennifer Aniston’s favorite workout platform – often with her adorable toddler by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.
